Purpose: To compare the visual and refractive outcomes, patient satisfaction and spectacle independence\nbetween three novel designs of diffractive IOLs. Method: Prospective study including\n150 patients with implantation of three IOLs: trifocal diffractive IOL AT LISA tri 839 MP (ATLISA, n\n= 50), trifocal diffractive IOL PhysIOL FineVision (FineVision, n = 50) and the extended range of vision\nIOL Tecnis Symfony ZRX00 (Symfony, n = 50). Patients were followed up for 6 months after\nsurgery. Major parameters were monocular and binocular uncorrected (UDVA) and corrected\n(CDVA) distance, uncorrected (UIVA) and distance corrected (DCIVA) intermediate (80 cm), and\nuncorrected (UNVA) and distance corrected (DCNVA) near (40 cm) visual acuities (UNVA), contrast\nsensitivity (CS), defocus curve as well as patient satisfaction and spectacle use. Results: Mean\npostoperative decimal UDVA was 1.01 for Symfony, 0.96 for ATLISA and 0.95 for the FineVision\nIOL. Postoperative UIVA was 0.95 with Symfony, 0.72 with ATLISA and 0.85 with the FineVision\nIOL. Postoperative UNVA was 0.96 with the FineVision, 0.72 with the ATLISA and 0.63 with the\nSymfony IOL. The Symfony defocus curve showed the smoothest profile. Mean mesopic CS was 0.84\nlog units with the Symfony, 0.83 with the ATLISA (0.83) and 0.65 with the FineVision IOL. Mean\nphotopic CS with the Symfony, ATLISA and FineVision was 1.05, 0.85 and 0.69 log units, respectively.\nTwenty percent of the patients with the ATLISA and FineVision IOLs and 5.6% of the Symfony\npatients reported halos and glare as troublesome or disabling. Reading glasses were frequently\nused by 5.6% of the Symfony patients. All patients with the trifocal IOLs reported to be\nspectacle-free for any distance. Conclusion: All 3 IOLs produce excellent results with high levels of\nspectacle independence. The Symfony produces better levels of distance and intermediate visual\nacuity, whereas the trifocal IOLs produced better near vision. Higher frequency of dysphotopsia\nwas seen with the trifocal IOLs.
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